Nanofabrication using an Electron Beam

The low electron dose and high resolution of TEM have permitted the imaging of polymer chains during specific beam manipulations that can actually control and fabricate at the nanoscale level. Such analyses with TEM heretofore have not been recognized for a variety of previously observed phenomena, and preconceived ideas regarding beam damage, thermal oxidation, free radical formation, and a host of other damaging conditions during electron irradiation have hindered progress in this field.  READ MORE

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Areas of Research: Basic Research

• The Structural/Molecular Mechanisms of Cellulose Biosynthesis in Bacteria, Algae, and Higher Plants
• Visualization of Molecular Structure Using High-Resolution Transmission Electron Microscopy Combined with Digital Image Analysis
• Airborne Algae
• Algal Viruses

Read more about this on the Basic Research page

Areas of Research: Applied Research

• Bio-Medical Engineering -- Medical Devices
• Materials Science -- Electronic Paper
• Materials Science -- Electron Beam Nanofabrication

Read more about this on the Applied Research page

Who We Are
We are a diverse group with diverse research interests. My students come from throughout the United States and from throughout the world: China, India, Thailand, Uzbekistan, ...
Colleagues who have studied in my laboratory have come from Japan, Sweden, France, Germany, Greece, Australia, Canada, ...

Read more about this on the Lab Profile Page

What We Have Done

• Golgi Structure and Function (1969)
   
• Cellulose Biosynthesis in Algae: first visualization of the linear complex in the cell membrane responsible for cellulose synthesis in Oocystis (1976). Subsequently we have studied and classified cellulose biosynthetic complexes (TCs) in a wide variety of algae, including Valonia, Boegesenia, Vaucheria, Erythrocladia, ___
   
• Cellulose Biosynthesis in Higher Plants: First visualization of the Cellulose Rosette: the biosynthetic complex in the cell membrane responsible for cellulose synthesis in corn (1976). Subsequently we have studied cellulose biosynthesis in other higher plants, including cotton, Arabidopsis, tobacco, and mung bean
   
• Cellulose Biosynthesis in Bacteria: Visualization of the Biosynthetic Complex Responsible for Cellulose synthesis in the bacterium Acetobacter xylinum (1976)
   
• Cellulose Biosynthesis in Bacteria: Cloning and sequencing of the cellulose synthase catalytic subunit gene of Acetobacter xylinum (1990)
   
• Cellulose Biosynthesis in Cyanobacteria

All of our publications are available online on the PUBLICATIONS PAGE

Contact Information

Prof. R. Malcolm Brown, Jr.

E-mail: rmbrown@mail.utexas.edu
Phone: (512) 471-3364

Mailing Address

The University of Texas at Austin
Molecular Genetics & Microbiology
1 University Station A5000
Austin, Texas 78712-0162