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Intellectual Property

THE LABORATORY OF R. MALCOLM BROWN, JR.


Patents Issued Patents Submitted Invention Disclosures
 


Patents -- Issued

  • Cellulose-Synthetic Composite Fibers. 1980. 
    U.S. Patent # 4,378,431
    Owned by The University of North Carolina.
     
  • Production of Microbial Cellulose. Roberts, Hardison, and Brown. 1984. 
    The University of Texas at Austin. 
    U.S. Patent Application Serial No. 684,844. UT/AUS:137.
    European Patent Application No 85309417.5 Publication number 0 186 495
     
  • Magnetic Alteration of Cellulose During its Biosynthesis. Brown, Brown, and Gretz. 
    U.S. Patent # 4,891,317.
    The University of Texas at Austin.
     
  • Microbial Cellulose Modified during Synthesis. Brown. Submitted, March 1987. 
    U.S. Patent # 4,950,597.
    The University of Texas at Austin. 
     
  • Multi-ribbon Microbial Cellulose. Brown and Lin. Submitted, March 1987.
    U.S. Patent # 4,943,439.
    The University of Texas at Austin. 
     
  • High Resolution Replicas. Brown and Mizuta. Submitted July, 1988.
    U.S. Patent # 4,967,825.
    The University of Texas at Austin. 
     
  • Modification of Cellulose Normally Synthesized by Cellulose-producing Microorganisms. Saxena, Roberts, and Brown. 1990. 
    U.S. Patent # 4,950,597
    The University of Texas at Austin. 
     
  • Enzymatic Method for Synthesis of Cellulose I. 1995. J. Lee, S. Kobayashi, S. Shoda, S. Kuga, K. Kudlicka, K. Okuda, L. Li, and R. M. Brown, Jr. 
    U.S. Patent # 5,472,859
    Owned by Inventors.
     
  • Recombinant Cellulose Synthase. I. Saxena, F.C. Lin, and R. M. Brown, Jr. Submitted. 1990. 
    U.S. Patent # 6,541,238.
    The University of Texas at Austin. 
     


Patents -- Submitted

  • Compositions, Methods, and Systems for making and using electronic paper. R. M. Brown and Jay Shah. October 1, 2003
    # 20050079386
    UTAU-1069.
     
  • High Resolution Low Dose Transmission Electron Microscopy Real-time Imaging and Manipulation of Nano-scale Objects in the Electron Beam. R. M. Brown, Jr., Zach Barnes, Tetsuo Kondo, and Chie Sawatari, 2004
    UTAU-1075.

 


Invention Disclosures

For licensing information about any of the technologies described below, contact:

The Office of Technology Commercialization
Licensing Associate
Phone: (512) 471-2995
E-mail: licensing@otc.utexas.edu 


Methods and Compositions for Improved Performance in Electronic Paper (OTC Project 1324-BL)  
AVAILABLE FOR LICENSING
Invention Description

The technique allows significant flexibility for display by greatly improving electronic paper through the use of microbial cellulose and electrochemical dyes. Strong chemical interactions between cellulose and the dyes have been demonstrated and eliminate the need for solvents. Dye migration problems have been eliminated, and activation by an electric field controls the images generated by the display device. Greater contrast is achieved through the discovery and manipulation of new forms of cellulose. 

Further, this technology involves connecting what looks like an ordinary hardback book with blank pages to a computer. The idea is to download original works or other text that would have hundreds of pages, each page being equal to a single computer LCD screen. Each page consists of millions of microscopic pixels of cellulose/ink combinations which can either reflect or absorb light. The result is a multi-page display which will be far more pleasing and easy on the eyes. Amazingly, cellulose, which has been used for centuries to record words and images, will still be the medium on which these books are distributed. 

The E-paper will require no power to maintain the static image once the display has been produced. Images on this revolutionary medium will be identical facsimiles of digitized information, either copied from original books or novel pages created entirely on a computer. Furthermore, the refresh rate of images will be sufficiently fast so that movies may be directly displayed on paper (when connected to a computer). In terms of its functionality, it will be identical to a book composed of materials made from cellulose, yet it will be remarkably reusable. 

Benefits
  • Reconfigurable
  • Good contrast and wide viewing angle
  • High brightness
  • Reduced weight and flexibility
  • No backlight required to read the screen
  • Better resolution/clarity (finer resolution than 72 pixels per inch) 
  • Uses 1/10,000 as much energy as an LCD screen
  • Thin and flexible
  • Biodegradable
  • Requires no deforestation

Features

  • The "paper" state is maintained (high reflectivity)
  • Color changes on a pixel level are homogeneous
  • Low potentials required
  • No power is required to maintain an image
  • Can image black-and-white or true-color images

Market Potential/Applications

The electronic paper revolution is predicted to span other types of electronic displays to replacing paper advertisement entirely, reducing printing and production costs. According to Economist Magazine, the market for point-of-sale advertising in America is worth $13 billion a year. However, the total estimated market for electronic paper is in the realm of $30 billion.

Development Stage/IP Status

Bench prototype completed
One U.S. Patent Application Filed. 

 
 
New Production Method for Novel Forms of Cellulose (OTC Project 1229-AL)  
AVAILABLE FOR LICENSING
Invention Description

Cellulose synthase genes have been stably integrated into the cyanobacteria chromosome through recombination. The use of cyanobacteria eliminates the need for a fixed carbon source and, in some cases, also eliminates the need for a fixed nitrogen source. Although cyanobacteria have been shown to synthesize cellulose, to date no cyanobacterium has demonstrated the ability to make cellulose at levels useful for commercial production. 

Benefits
  • Can efficiently produce large amounts of cellulose
  • Never-dried bacterial cellulose can be processed into any shape
  • Can be used as a material in a variety of applications

Features

  • Cellulose synthase genes have been stably integrated into the chromosome of cyanobacteria
  • No need for carbon or nitrogen source in the production of bacterial cellulose
  • High salt tolerance

Market Potential/Applications

Allows for the production of a large scale, global cellulose crop that can be used in a variety of applications. 

Development Stage/IP Status

U.S. Patent Issued: 6,541,238
15 Foreign Applications Pending


 
Uranyl Acetate Deposition as a Method of Molecular Structure Determination  (OTC Project 1231-AL)  
AVAILABLE FOR LICENSING
Invention Description

This invention provides a quick and accurate method for the determination of molecular structures using uranyl acetate. Using a transmission electron microscope electron beam, uranium atoms from uranyl acetate can crystallize over a substrate. The pattern of these crystals can be used to determine the structure of the substrate. Using this technique, the details of single molecules can accurately be imaged at a resolution nearly comparable to X-ray analysis. This method provides for the quick and easy examination of biological complexes in multiple states.


 
Manipulation of Nano-Scale Objects Using High-Resolution, Low-Dose Transmission Electron Microscopy (OTC Project 1207-AL)  
AVAILABLE FOR LICENSING
  Invention Description

This technology encompasses a new type of microscopy that provides for extreme visualization and the manipulation of single-polymer chains in real-time while imaging them in the transmission electron microscope (TEM). The capability to synthesize a product while simultaneously observing its fabrication is a first. Additionally, this invention provides for much greater control for the purpose of manipulation and synthesis of nanomaterials from a variety of sources. The low-dose electron beam allows nanofabrication of significantly smaller structures from polymeric materials. The capability to manipulate, synthesize, and analyze a material simultaneously changes the TEM's role in research development and the production of a variety of scientific and commercial products. 

Benefits

  • Provides for significantly smaller, nanometer-sized fabrication
  • Nanofabrication can proceed from a variety of materials including biological and inorganic
  • Low-dose electron beams do not destroy the samples

Features

  • Real-time monitoring
  • Differential control
  • Formation of nanopatterns through the crystallization of uranyl acetate using an electron beam

Market Potential/Applications

The world microscopy market is currently over $1.5 billion and is expected to rise steadily as new applications in medical imaging and nanotechnology are explored. Microscopes (such as this) used in the manipulation of materials could account for sales upwards of $775 million over the next two years.

Development Stage/IP Status

Lab/bench prototype completed;
Two U.S. Patent Applications Filed.

   
 
 
   
   
   


 

Patents Issued Patents Submitted Invention Disclosures

 

page updated 15-Dec-2006