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186. Abstract
The discovery of a large number of genes encoding cellulose synthases and related glycosyltransferases in plants has led to a renewed interest in the biosynthesis of cell-wall polysaccharides. A number of approaches, including virus-induced gene silencing have proven useful in the functional analysis of these genes. X-ray analysis of the structures of a few glycosyltransferases has led to the identification and confirmation of the role of conserved residues within this group of enzymes. Analysis of related enzymes has provided useful information on the possible domain organization of cellulose synthases and the requirement for at least two separate glycosyltransferase activities in the processive synthesis of sugar chains.
Abbreviations: Ces cellulose synthase; CR-P conserved plant specific;
Csl cellulose-synthase-like; dp degree of polymerization; EST expressed
sequence tag; Gsl glucan-synthase-like; HA hyaluronan; HAS HA synthase;
irx3 irregular xylem 3; rsw1 radial swelling 1; TC terminal complex
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Last modified April 29, 2008
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Malcolm Brown, Jr.